Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | cytidine deaminase | 0.0122 | 1 | 1 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0025 | 0.0195 | 0.0195 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0023 | 0 | 0.5 |
Giardia lamblia | Cytidine deaminase | 0.0122 | 1 | 1 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0025 | 0.0195 | 0.0195 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0023 | 0 | 0.5 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.0122 | 1 | 1 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0122 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0025 | 0.0195 | 0.0195 |
Trypanosoma brucei | RNA helicase, putative | 0.0086 | 0.6312 | 0.6312 |
Mycobacterium ulcerans | cytidine deaminase | 0.0122 | 1 | 0.5 |
Onchocerca volvulus | 0.0122 | 1 | 1 | |
Trichomonas vaginalis | cytidine deaminase, putative | 0.0122 | 1 | 1 |
Onchocerca volvulus | 0.0122 | 1 | 1 | |
Leishmania major | cytidine deaminase-like protein | 0.0122 | 1 | 1 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.0122 | 1 | 1 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.0122 | 1 | 1 |
Mycobacterium leprae | PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) | 0.0122 | 1 | 0.5 |
Entamoeba histolytica | cytidine deaminase, putative | 0.0122 | 1 | 0.5 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0025 | 0.0195 | 0.0195 |
Echinococcus multilocularis | cytidine deaminase | 0.0122 | 1 | 1 |
Echinococcus granulosus | cytidine deaminase | 0.0122 | 1 | 1 |
Trypanosoma brucei | unspecified product | 0.0025 | 0.0195 | 0.0195 |
Schistosoma mansoni | hypothetical protein | 0.0086 | 0.6312 | 1 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.0122 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.