Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | fatty acid binding protein | 0.0602 | 1 | 1 |
Schistosoma mansoni | fatty acid binding protein | 0.0602 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0436 | 0.6552 | 0.6454 |
Loa Loa (eye worm) | hypothetical protein | 0.0135 | 0.0274 | 0.0274 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0436 | 0.6552 | 0.6454 |
Loa Loa (eye worm) | hypothetical protein | 0.0436 | 0.6552 | 0.6552 |
Loa Loa (eye worm) | lipocalin/cytosolic fatty-acid binding protein family protein | 0.0602 | 1 | 1 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0436 | 0.6552 | 0.6454 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0602 | 1 | 1 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0602 | 1 | 1 |
Echinococcus multilocularis | fatty acid binding protein FABP2 | 0.0602 | 1 | 1 |
Echinococcus granulosus | fatty acid binding protein FABP2 | 0.0602 | 1 | 1 |
Onchocerca volvulus | 0.0436 | 0.6552 | 0.5 | |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0436 | 0.6552 | 0.6454 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0436 | 0.6552 | 0.6454 |
Loa Loa (eye worm) | hypothetical protein | 0.0436 | 0.6552 | 0.6552 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0436 | 0.6552 | 0.6454 |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0436 | 0.6552 | 0.6454 |
Onchocerca volvulus | Deterin homolog | 0.0436 | 0.6552 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.