Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | prostaglandin E receptor 2 (subtype EP2), 53kDa | Starlite/ChEMBL | References |
Homo sapiens | prostaglandin E receptor 4 (subtype EP4) | Starlite/ChEMBL | References |
Homo sapiens | prostaglandin E receptor 3 (subtype EP3) | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 0.084 uM | Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 0.084 uM | Affinity at human Prostanoid EP3 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 0.83 uM | Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 0.83 uM | Affinity at human Prostanoid EP2 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 1.7 uM | Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 1.7 uM | Affinity at human Prostanoid EP4 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 72 uM | Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Ki (binding) | = 72 uM | Affinity at human Prostanoid EP1 receptor in the human embryonic kidney (HEK) 293 cell line. | ChEMBL. | 14552786 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.