Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | insulin-like growth factor binding protein 1 | Starlite/ChEMBL | References |
Homo sapiens | insulin-like growth factor binding protein 2, 36kDa | Starlite/ChEMBL | References |
Homo sapiens | insulin-like growth factor binding protein 5 | Starlite/ChEMBL | References |
Homo sapiens | insulin-like growth factor binding protein 3 | Starlite/ChEMBL | References |
Homo sapiens | insulin-like growth factor binding protein 4 | Starlite/ChEMBL | References |
Homo sapiens | insulin-like growth factor binding protein 6 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | insulin-like growth factor binding protein-related | 0.0334 | 0.5 | 0.5 |
Echinococcus multilocularis | insulin growth factor binding | 0.0334 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 6.23 nM | The compound was tested for binding affinity against Insulin-like growth factor binding protein 4 | ChEMBL. | 11689087 |
Ki (binding) | = 6.23 nM | The compound was tested for binding affinity against Insulin-like growth factor binding protein 4 | ChEMBL. | 11689087 |
Ki (binding) | = 17.13 nM | The compound was tested for binding affinity against insulin-like growth factor binding protein 2 | ChEMBL. | 11689087 |
Ki (binding) | = 17.13 nM | The compound was tested for binding affinity against insulin-like growth factor binding protein 2 | ChEMBL. | 11689087 |
Ki (binding) | = 20.95 nM | The compound was tested for binding affinity against Insulin-like growth factor binding protein 5 | ChEMBL. | 11689087 |
Ki (binding) | = 20.95 nM | The compound was tested for binding affinity against Insulin-like growth factor binding protein 5 | ChEMBL. | 11689087 |
Ki (binding) | = 28 nM | Inhibitory activity against Insulin-like growth factor binding protein 3 | ChEMBL. | 11689087 |
Ki (binding) | = 28 nM | Inhibitory activity against Insulin-like growth factor binding protein 3 | ChEMBL. | 11689087 |
Ki (binding) | = 34.23 nM | The compound was tested for binding affinity against insulin-like growth factor binding protein 1 | ChEMBL. | 11689087 |
Ki (binding) | = 34.23 nM | The compound was tested for binding affinity against insulin-like growth factor binding protein 1 | ChEMBL. | 11689087 |
Ki (binding) | = 84.65 nM | The compound was tested for binding affinity against Insulin-like growth factor binding protein 6 | ChEMBL. | 11689087 |
Ki (binding) | = 84.6500000000001 nM | The compound was tested for binding affinity against Insulin-like growth factor binding protein 6 | ChEMBL. | 11689087 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.