Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | chemokine (C-C motif) receptor 2 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | phosphoglucomutase | 0.0112 | 0.33 | 0.2567 |
Brugia malayi | RNase H family protein | 0.0066 | 0.0985 | 0.1733 |
Echinococcus multilocularis | ribonuclease H1 | 0.0112 | 0.33 | 0.3613 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0113 | 0.3372 | 0.5 |
Toxoplasma gondii | ribonuclease HI protein | 0.0113 | 0.3372 | 0.5 |
Schistosoma mansoni | phosphoglucomutase | 0.0112 | 0.33 | 0.2567 |
Brugia malayi | RNase H family protein | 0.0159 | 0.5687 | 1 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0159 | 0.5687 | 0.5 |
Trichomonas vaginalis | ribonuclease H1, putative | 0.0113 | 0.3372 | 0.5 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0227 | 0.9133 | 1 |
Entamoeba histolytica | ribonuclease, putative | 0.0046 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0 | 0.5 |
Trypanosoma brucei | ribonuclease H1 | 0.0159 | 0.5687 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0245 | 1 | 1 |
Leishmania major | ribonuclease H1, putative | 0.0113 | 0.3372 | 0.5 |
Onchocerca volvulus | Ribonuclease H1 homolog | 0.0066 | 0.0985 | 1 |
Echinococcus granulosus | ribonuclease H1 | 0.0112 | 0.33 | 0.33 |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0113 | 0.3372 | 0.5 |
Giardia lamblia | Ribonuclease H | 0.0113 | 0.3372 | 0.5 |
Brugia malayi | RNase H family protein | 0.0066 | 0.0985 | 0.1733 |
Trypanosoma cruzi | ribonuclease H1, putative | 0.0159 | 0.5687 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.