Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.05 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus UC-76 | ChEMBL. | 8277495 |
MIC (functional) | = 0.1 ug ml-1 | Minimum inhibitory concentration against Enterobacteriaceae cloacae MA-2646 | ChEMBL. | 8277495 |
MIC (functional) | = 0.1 ug ml-1 | Minimum inhibitory concentration against Escherichia coli Vogel | ChEMBL. | 8277495 |
MIC (functional) | = 0.1 ug ml-1 | Minimum inhibitory concentration against Staphylococcus aureus H-228 | ChEMBL. | 8277495 |
MIC (functional) | = 0.1 ug ml-1 | Minimum inhibitory concentration against Streptococcus pneumoniae SV-1 | ChEMBL. | 8277495 |
MIC (functional) | = 0.1 ug ml-1 | Minimum inhibitory concentration against Streptococcus pyogenes C-203 | ChEMBL. | 8277495 |
MIC (functional) | = 0.1 ug ml-1 | Minimum inhibitory concentration against Escherichia coli Vogel | ChEMBL. | 8277495 |
MIC (functional) | = 0.2 ug ml-1 | Minimum inhibitory concentration against Klebsiella pneumoniae MGH-2 | ChEMBL. | 8277495 |
MIC (functional) | = 0.2 ug ml-1 | Minimum inhibitory concentration against Enterobacteriaceae faecalis MGH-2 | ChEMBL. | 8277495 |
MIC (functional) | = 0.4 ug ml-1 | Minimum inhibitory concentration against Providencia rettgeri M-1771 | ChEMBL. | 8277495 |
MIC (functional) | = 1.6 ug ml-1 | Minimum inhibitory concentration against Pseudomonas aeruginosa UI-18 | ChEMBL. | 8277495 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.