Detailed information for compound 23023

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 763.878 | Formula: C36H57N7O11
  • H donors: 9 H acceptors: 11 LogP: -1.19 Rotable bonds: 27
    Rule of 5 violations (Lipinski): 4
  • SMILES: OC(=O)C[C@@H](C(=O)N[C@H](C(=O)O)CC(C)(C)C)NC(=O)[C@H](CC(=O)N(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccc(cc1)O)N
  • InChi: 1S/C36H57N7O11/c1-18(2)28(42-34(52)29(19(3)4)41-30(48)22(37)14-20-10-12-21(44)13-11-20)33(51)39-23(15-26(45)43(8)9)31(49)38-24(16-27(46)47)32(50)40-25(35(53)54)17-36(5,6)7/h10-13,18-19,22-25,28-29,44H,14-17,37H2,1-9H3,(H,38,49)(H,39,51)(H,40,50)(H,41,48)(H,42,52)(H,46,47)(H,53,54)/t22-,23-,24-,25-,28-,29-/m0/s1
  • InChiKey: QCUFMVVWFUYWRO-LMXVXWCUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus fmrfamide receptor 0.0342 0.0139 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0342 0.0139 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0342 0.0139 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0342 0.0139 1
Mycobacterium tuberculosis Probable histidinol dehydrogenase HisD (HDH) 1.5692 1 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0342 0.0139 0.2516
Schistosoma mansoni biogenic amine receptor 0.0342 0.0139 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus granulosus neuropeptide receptor 0.0342 0.0139 1
Brugia malayi G-protein coupled receptor 0.0342 0.0139 0.2516
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni biogenic amine (5HT) receptor 0.0342 0.0139 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0342 0.0139 0.5
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0342 0.0139 0.2516
Echinococcus granulosus neuropeptide Y receptor 0.0342 0.0139 1
Echinococcus multilocularis somatostatin receptor 0.0342 0.0139 1
Loa Loa (eye worm) G-protein coupled receptor 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni adenoreceptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus sex peptide receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0342 0.0139 1
Brugia malayi larval opioid receptor 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide Y receptor 0.0342 0.0139 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide s receptor 0.0342 0.0139 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0784 0.0423 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus serotonin receptor 0.0342 0.0139 1
Echinococcus granulosus tm gpcr rhodopsin 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide receptor 0.0342 0.0139 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus orexin receptor type 2 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide receptor 0.0342 0.0139 1
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0784 0.0423 1
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Brugia malayi Melatonin receptor type 1A 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Schistosoma mansoni opsin-like receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0342 0.0139 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0342 0.0139 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0342 0.0139 1
Loa Loa (eye worm) neuropeptide F receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis g protein coupled receptor 0.0342 0.0139 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi putative neuropeptide receptor 0.0342 0.0139 0.2516
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0342 0.0139 0.2516
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis fmrfamide receptor 0.0342 0.0139 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0342 0.0139 1
Schistosoma mansoni neuropeptide F-like receptor 0.0342 0.0139 1
Loa Loa (eye worm) TYRA-2 protein 0.0342 0.0139 0.2516
Echinococcus granulosus tachykinin peptides receptor 99D 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0342 0.0139 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni biogenic amine (5HT) receptor 0.0342 0.0139 1
Echinococcus granulosus neuropeptide receptor A26 0.0342 0.0139 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi Serotonin receptor 0.0342 0.0139 0.2516
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0342 0.0139 1
Echinococcus granulosus g-protein coupled receptor 0.0342 0.0139 1
Brugia malayi G protein-coupled receptor 0.0342 0.0139 0.2516
Schistosoma mansoni myosin xvIII 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide Y receptor 0.0342 0.0139 1
Echinococcus granulosus g protein coupled receptor 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus multilocularis g protein coupled receptor 0.0342 0.0139 1
Schistosoma mansoni opsin-like receptor 0.0342 0.0139 1
Echinococcus granulosus tm gpcr rhodopsin 0.0342 0.0139 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0342 0.0139 0.2516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus neuropeptide Y receptor 0.0342 0.0139 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi Dopamine receptor 0.0342 0.0139 0.2516
Brugia malayi ORL1-like opioid receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis allatostatin A receptor 0.0342 0.0139 1
Echinococcus granulosus allatostatin A receptor 0.0342 0.0139 1
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis dro:myosuppressin receptor 0.0342 0.0139 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus neuropeptides capa receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0342 0.0139 0.2516
Brugia malayi putative neuropeptide receptor NPR1 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide receptor A26 0.0342 0.0139 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0342 0.0139 1
Brugia malayi follicle stimulating hormone receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis G protein coupled receptor 139 0.0342 0.0139 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni biogenic amine receptor 0.0342 0.0139 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0342 0.0139 1
Brugia malayi AKH receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) neuropeptide F receptor 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis g protein coupled receptor 0.0342 0.0139 1
Loa Loa (eye worm) G-protein coupled receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus dro:myosuppressin receptor 0.0342 0.0139 1
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0342 0.0139 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0342 0.0139 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0342 0.0139 1
Echinococcus granulosus hypothetical protein 0.0342 0.0139 1
Echinococcus granulosus G protein coupled receptor 139 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis neuropeptides capa receptor 0.0342 0.0139 1
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus multilocularis orexin receptor type 2 0.0342 0.0139 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0342 0.0139 0.2516
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0342 0.0139 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0342 0.0139 1
Schistosoma mansoni neuropeptide F-like receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Onchocerca volvulus Neuropeptide F receptor homolog 0.0342 0.0139 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.0342 0.0139 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0342 0.0139 1
Echinococcus multilocularis serotonin receptor 0.0342 0.0139 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0342 0.0139 1
Echinococcus granulosus neuropeptide s receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi Dopamine receptor protein 2 0.0342 0.0139 0.2516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0342 0.0139 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Mycobacterium ulcerans histidinol dehydrogenase 1.5692 1 0.5
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Brugia malayi neuropeptide F receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0342 0.0139 1
Echinococcus multilocularis neuropeptides capa receptor 0.0342 0.0139 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0342 0.0139 1
Echinococcus granulosus g protein coupled receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis serotonin receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi sulfakinin receptor protein 0.0342 0.0139 0.2516
Brugia malayi G protein-coupled receptor F59B2.13 0.0342 0.0139 0.2516
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus peptide allatostatin:somatostatin 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Leishmania major C-8 sterol isomerase-like protein 0.0784 0.0423 0.5
Brugia malayi neuropeptide F receptor 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi G-protein coupled receptor 0.0342 0.0139 0.2516
Brugia malayi Serotonin receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0401 0.0177 0.3509
Echinococcus multilocularis g-protein coupled receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Trypanosoma brucei C-8 sterol isomerase, putative 0.0784 0.0423 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni histamine h1 receptor 0.0342 0.0139 1
Echinococcus multilocularis fmrfamide receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni opsin-like receptor 0.0342 0.0139 1
Echinococcus granulosus somatostatin receptor 0.0342 0.0139 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0784 0.0423 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0342 0.0139 0.2516
Brugia malayi Dopamine receptor protein 1 0.0342 0.0139 0.2516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi Tachykinin-like peptides receptor 99D 0.0342 0.0139 0.2516
Brugia malayi RE15519p 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis G-protein coupled receptor, putative 0.0342 0.0139 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0342 0.0139 0.2516
Echinococcus granulosus neuropeptide receptor 0.0342 0.0139 1
Echinococcus granulosus tm gpcr rhodopsin 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi GnHR receptor homolog 0.0342 0.0139 0.2516
Echinococcus granulosus g protein coupled receptor 0.0342 0.0139 1
Schistosoma mansoni biogenic amine receptor 0.0342 0.0139 1
Echinococcus multilocularis sex peptide receptor 0.0342 0.0139 1
Echinococcus granulosus neuropeptides capa receptor 0.0342 0.0139 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.2 uM The compound was tested in vitro for inhibitory activity against Herpes Simplex Virus type 2 ribonucleotide reductase ChEMBL. No reference
IC50 (binding) = 22 uM Inhibitory activity of YAGAVVNDL against Herpes Simplex Virus type 2 (HSV-2) ribonucleotide reductase determined as control ChEMBL. No reference
Relative potency (binding) = 110 Relative potency of the compound to that of YAGAVVNDL against Herpes Simplex Virus type 2 ribonucleotide reductase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

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