Detailed information for compound 23051

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 763.878 | Formula: C36H57N7O11
  • H donors: 9 H acceptors: 11 LogP: -1.22 Rotable bonds: 28
    Rule of 5 violations (Lipinski): 4
  • SMILES: CCN(C(=O)C[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CC(C)C)CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](Cc1ccc(cc1)O)N)C
  • InChi: 1S/C36H57N7O11/c1-9-43(8)27(45)16-24(32(49)38-25(17-28(46)47)33(50)40-26(36(53)54)14-18(2)3)39-34(51)29(19(4)5)42-35(52)30(20(6)7)41-31(48)23(37)15-21-10-12-22(44)13-11-21/h10-13,18-20,23-26,29-30,44H,9,14-17,37H2,1-8H3,(H,38,49)(H,39,51)(H,40,50)(H,41,48)(H,42,52)(H,46,47)(H,53,54)/t23-,24-,25-,26-,29-,30-/m0/s1
  • InChiKey: KLTFTYHOIYTGAF-SUAVODKESA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis G protein coupled receptor 139 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi follicle stimulating hormone receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide receptor A26 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Brugia malayi putative neuropeptide receptor NPR1 0.0342 0.0139 0.2516
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0342 0.0139 0.2516
Echinococcus granulosus neuropeptides capa receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0342 0.0139 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus allatostatin A receptor 0.0342 0.0139 1
Echinococcus multilocularis allatostatin A receptor 0.0342 0.0139 1
Brugia malayi ORL1-like opioid receptor 0.0342 0.0139 0.2516
Brugia malayi Dopamine receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0342 0.0139 1
Echinococcus granulosus neuropeptide Y receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0342 0.0139 0.2516
Echinococcus granulosus tm gpcr rhodopsin 0.0342 0.0139 1
Echinococcus multilocularis g protein coupled receptor 0.0342 0.0139 1
Schistosoma mansoni opsin-like receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus g protein coupled receptor 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide Y receptor 0.0342 0.0139 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni myosin xvIII 0.0342 0.0139 1
Brugia malayi G protein-coupled receptor 0.0342 0.0139 0.2516
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0342 0.0139 1
Echinococcus granulosus g-protein coupled receptor 0.0342 0.0139 1
Brugia malayi Serotonin receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0342 0.0139 1
Echinococcus granulosus neuropeptide receptor A26 0.0342 0.0139 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0342 0.0139 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0342 0.0139 1
Echinococcus granulosus tachykinin peptides receptor 99D 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Loa Loa (eye worm) TYRA-2 protein 0.0342 0.0139 0.2516
Schistosoma mansoni neuropeptide F-like receptor 0.0342 0.0139 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0342 0.0139 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis fmrfamide receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0342 0.0139 0.2516
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0342 0.0139 1
Brugia malayi putative neuropeptide receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) melatonin receptor type 1A 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Loa Loa (eye worm) neuropeptide F receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0342 0.0139 1
Echinococcus multilocularis g protein coupled receptor 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0342 0.0139 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni opsin-like receptor 0.0342 0.0139 1
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi Melatonin receptor type 1A 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0784 0.0423 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus orexin receptor type 2 0.0342 0.0139 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide receptor 0.0342 0.0139 1
Echinococcus granulosus tm gpcr rhodopsin 0.0342 0.0139 1
Echinococcus granulosus serotonin receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0784 0.0423 1
Echinococcus multilocularis neuropeptide s receptor 0.0342 0.0139 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide Y receptor 0.0342 0.0139 1
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi larval opioid receptor 0.0342 0.0139 0.2516
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus granulosus sex peptide receptor 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni adenoreceptor 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) G-protein coupled receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis somatostatin receptor 0.0342 0.0139 1
Echinococcus granulosus neuropeptide Y receptor 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0342 0.0139 0.5
Schistosoma mansoni biogenic amine (5HT) receptor 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi G-protein coupled receptor 0.0342 0.0139 0.2516
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus neuropeptide receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0342 0.0139 1
Schistosoma mansoni biogenic amine receptor 0.0342 0.0139 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0342 0.0139 0.2516
Mycobacterium tuberculosis Probable histidinol dehydrogenase HisD (HDH) 1.5692 1 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0342 0.0139 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0342 0.0139 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0342 0.0139 1
Echinococcus granulosus fmrfamide receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus neuropeptides capa receptor 0.0342 0.0139 1
Echinococcus multilocularis sex peptide receptor 0.0342 0.0139 1
Schistosoma mansoni biogenic amine receptor 0.0342 0.0139 1
Echinococcus granulosus g protein coupled receptor 0.0342 0.0139 1
Brugia malayi GnHR receptor homolog 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus tm gpcr rhodopsin 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus neuropeptide receptor 0.0342 0.0139 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0342 0.0139 0.2516
Echinococcus multilocularis G-protein coupled receptor, putative 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi RE15519p 0.0342 0.0139 0.2516
Brugia malayi Tachykinin-like peptides receptor 99D 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Brugia malayi Dopamine receptor protein 1 0.0342 0.0139 0.2516
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0342 0.0139 0.2516
Echinococcus granulosus 7tm_1 domain containing protein 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0784 0.0423 1
Schistosoma mansoni opsin-like receptor 0.0342 0.0139 1
Echinococcus granulosus somatostatin receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis fmrfamide receptor 0.0342 0.0139 1
Schistosoma mansoni histamine h1 receptor 0.0342 0.0139 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Trypanosoma brucei C-8 sterol isomerase, putative 0.0784 0.0423 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis g-protein coupled receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0401 0.0177 0.3509
Brugia malayi Serotonin receptor 0.0342 0.0139 0.2516
Brugia malayi G-protein coupled receptor 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi neuropeptide F receptor 0.0342 0.0139 0.2516
Leishmania major C-8 sterol isomerase-like protein 0.0784 0.0423 0.5
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus peptide allatostatin:somatostatin 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni growth hormone secretagogue receptor 0.0342 0.0139 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0342 0.0139 0.2516
Brugia malayi sulfakinin receptor protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis serotonin receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus granulosus g protein coupled receptor 0.0342 0.0139 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0342 0.0139 1
Echinococcus multilocularis neuropeptides capa receptor 0.0342 0.0139 1
Brugia malayi neuropeptide F receptor 0.0342 0.0139 0.2516
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Mycobacterium ulcerans histidinol dehydrogenase 1.5692 1 0.5
Onchocerca volvulus 0.0342 0.0139 0.5
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0342 0.0139 0.2516
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0342 0.0139 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Brugia malayi Dopamine receptor protein 2 0.0342 0.0139 0.2516
Echinococcus granulosus neuropeptide s receptor 0.0342 0.0139 1
Echinococcus multilocularis serotonin receptor 0.0342 0.0139 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0342 0.0139 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0342 0.0139 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0342 0.0139 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0342 0.0139 0.5
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0342 0.0139 1
Schistosoma mansoni amine GPCR 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni neuropeptide F-like receptor 0.0342 0.0139 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0342 0.0139 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0342 0.0139 0.2516
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0342 0.0139 1
Echinococcus multilocularis orexin receptor type 2 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni hypothetical protein 0.0342 0.0139 1
Echinococcus multilocularis neuropeptides capa receptor 0.0342 0.0139 1
Echinococcus granulosus G protein coupled receptor 139 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Echinococcus granulosus hypothetical protein 0.0342 0.0139 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0342 0.0139 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0342 0.0139 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0342 0.0139 1
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Echinococcus granulosus dro:myosuppressin receptor 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) G-protein coupled receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis g protein coupled receptor 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Loa Loa (eye worm) neuropeptide F receptor 0.0342 0.0139 0.2516
Brugia malayi AKH receptor 0.0342 0.0139 0.2516
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0342 0.0139 1
Loa Loa (eye worm) hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni neuropeptide receptor 0.0342 0.0139 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0342 0.0139 1
Brugia malayi hypothetical protein 0.0342 0.0139 0.2516
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0342 0.0139 1
Schistosoma mansoni biogenic amine receptor 0.0342 0.0139 1
Onchocerca volvulus 0.0342 0.0139 0.5
Onchocerca volvulus 0.0342 0.0139 0.5
Schistosoma mansoni amine GPCR 0.0342 0.0139 1

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.4 uM The compound was tested in vitro for inhibitory activity against Herpes Simplex Virus type 2 ribonucleotide reductase ChEMBL. No reference
IC50 (binding) = 10 uM Inhibitory activity of YAGAVVNDL against Herpes Simplex Virus type 2 (HSV-2) ribonucleotide reductase determined as control ChEMBL. No reference
Relative potency (binding) = 25 Relative potency of the compound to that of YAGAVVNDL against Herpes Simplex Virus type 2 ribonucleotide reductase ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.