Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glutamate receptor 2 | 0.0125 | 0.185 | 0.193 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0173 | 0.344 | 1 |
Schistosoma mansoni | glutamate receptor kainate | 0.0173 | 0.344 | 0.344 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0194 | 0.4147 | 0.4326 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0194 | 0.4147 | 0.4326 |
Schistosoma mansoni | glutamate receptor kainate | 0.0173 | 0.344 | 0.344 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0176 | 0.3557 | 0.371 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0173 | 0.344 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0173 | 0.344 | 0.3589 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0267 | 0.656 | 0.6843 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0194 | 0.4147 | 0.4326 |
Schistosoma mansoni | glutamate receptor kainate | 0.0173 | 0.344 | 0.344 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0194 | 0.4147 | 0.4326 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0358 | 0.9586 | 1 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0176 | 0.3557 | 0.371 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0194 | 0.4147 | 0.4326 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0194 | 0.4147 | 0.4326 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0173 | 0.344 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0194 | 0.4147 | 0.4326 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0267 | 0.656 | 0.6843 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0173 | 0.344 | 0.344 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0198 | 0.4263 | 0.4447 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0173 | 0.344 | 1 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0125 | 0.185 | 0.193 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0358 | 0.9586 | 0.9586 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0173 | 0.344 | 0.344 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0198 | 0.4263 | 0.4447 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0091 | 0.0706 | 0.0737 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0358 | 0.9586 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0194 | 0.4147 | 0.4326 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0194 | 0.4147 | 0.4326 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0194 | 0.4147 | 0.4326 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0173 | 0.344 | 0.344 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Bioreduction (functional) | = 0 % | Bioreduction experiment was conducted by incubation of the sulfoxides with rat liver S-9 fractions in anaerobic conditions N2) | ChEMBL. | 11063612 |
Bioreduction (functional) | = 0 % | Bioreduction experiment was conducted by incubation of the sulfoxides with rat liver S-9 fractions in anaerobic conditions (N2, without cofactors) | ChEMBL. | 11063612 |
Bioreduction (functional) | = 4.4 % | Bioreduction experiment was conducted by incubation of the sulfoxides with rat liver S-9 fractions in anaerobic conditions (N2, benzaldehyde) | ChEMBL. | 11063612 |
E (functional) | = 1.82 -V | Reduction potential (SCE) determined by differential pulse polarography of the sulfoxides with rat liver S-9 fractions | ChEMBL. | 11063612 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.