Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | sodium-bile acid cotransporter related | 0.2844 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0049 | 0.0049 |
Schistosoma mansoni | sodium-bile acid cotransporter | 0.1691 | 0.5872 | 0.5852 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0049 | 0.0049 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0049 | 0.0049 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.2844 | 1 | 1 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.2844 | 1 | 1 |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.2844 | 1 | 1 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.2844 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0049 | 0.0049 |
Onchocerca volvulus | 0.2844 | 1 | 0.5 | |
Echinococcus multilocularis | sodium bile acid cotransporter | 0.2844 | 1 | 1 |
Echinococcus granulosus | sodium bile acid cotransporter | 0.2844 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2844 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0049 | 0.0049 |
Schistosoma mansoni | sodium-bile acid cotransporter related | 0.1153 | 0.3948 | 0.3919 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0049 | 0.0049 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
RBA (binding) | = 29.4 % | Relative binding affinity (RBA) towards estrogen receptor. | ChEMBL. | 7990116 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.