Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Geometric mean (functional) | = 76.109 | Geometric mean of antibacterial activity (Gram -ve bacteria) of the compound | ChEMBL. | 8558512 |
Geometric mean (functional) | = 84.448 | Geometric mean of antibacterial activity (Gram +ve bacteria) of the compound | ChEMBL. | 8558512 |
MIC (functional) | = 16 ug ml-1 | Antibacterial activity of the compound tested against E. coli ISF 432 | ChEMBL. | 8558512 |
MIC (functional) | = 16 ug ml-1 | Antibacterial activity of the compound tested against K. pneumoniae (Klebsiella pneumoniae) ATCC10031 | ChEMBL. | 8558512 |
MIC (functional) | = 16 ug ml-1 | Antibacterial activity of the compound tested against E. coli ISF 432 | ChEMBL. | 8558512 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against Staphylococcus aureus MPR 5 | ChEMBL. | 8558512 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity against Staphylococcus aureus ATCC6538 | ChEMBL. | 8558512 |
MIC (functional) | = 64 ug ml-1 | Antibacterial activity tested against Staphylococcus epidermidis HCF Berset C | ChEMBL. | 8558512 |
MIC (functional) | > 128 ug ml-1 | Antibacterial activity of the compound tested against E. coli ATCC 8739 | ChEMBL. | 8558512 |
MIC (functional) | > 128 ug ml-1 | Antibacterial activity of the compound tested against Enterobacter cloacae OMNFI 174 | ChEMBL. | 8558512 |
MIC (functional) | = 128 ug ml-1 | Antibacterial activity tested against Proteus vulgaris CNUR 5 | ChEMBL. | 8558512 |
MIC (functional) | = 128 ug ml-1 | Antibacterial activity tested against Providencia stuartii CNUR 5 | ChEMBL. | 8558512 |
MIC (functional) | > 128 ug ml-1 | Antibacterial activity tested against Shigella enteritidis | ChEMBL. | 8558512 |
MIC (functional) | > 128 ug ml-1 | Antibacterial activity of the compound tested against P. ae (Pseudomonas aeruginosa) ATCC 9027 | ChEMBL. | 8558512 |
MIC (functional) | = 128 ug ml-1 | Antibacterial activity tested against Staphylococcus epidermidis CPHL A2 | ChEMBL. | 8558512 |
MIC (functional) | = 128 ug ml-1 | Antibacterial activity tested against Streptococcus faecalis LEP Br | ChEMBL. | 8558512 |
MIC (functional) | > 128 ug ml-1 | Antibacterial activity of the compound tested against E. coli ATCC 8739 | ChEMBL. | 8558512 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.