Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Matrixin family protein | 0.0272 | 0.0614 | 0.1085 |
Onchocerca volvulus | 0.0385 | 0.2102 | 0.3431 | |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0603 | 0.4951 | 1 |
Loa Loa (eye worm) | matrix metalloproteinase | 0.0272 | 0.0614 | 0.1085 |
Brugia malayi | Matrix metalloprotease, N-terminal domain containing protein | 0.0331 | 0.139 | 0.2455 |
Mycobacterium tuberculosis | Probable peptidoglycan hydrolase | 0.0331 | 0.139 | 0.5 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.061 | 0.5053 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.0614 | 0.1085 |
Plasmodium vivax | transporter, putative | 0.061 | 0.5053 | 0.5 |
Loa Loa (eye worm) | matrixin family protein | 0.0657 | 0.5663 | 1 |
Brugia malayi | Matrixin family protein | 0.0272 | 0.0614 | 0.1085 |
Brugia malayi | Matrixin family protein | 0.0272 | 0.0614 | 0.1085 |
Brugia malayi | Matrixin family protein | 0.0272 | 0.0614 | 0.1085 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.0614 | 0.1085 |
Brugia malayi | Hemopexin family protein | 0.0385 | 0.2102 | 0.3712 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0988 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.061 | 0.5053 | 0.5 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0766 | 0.7096 | 0.7096 |
Schistosoma mansoni | matrix metallopeptidase-9 (M10 family) | 0.0278 | 0.0701 | 0.3336 |
Brugia malayi | Matrixin family protein | 0.0657 | 0.5663 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.061 | 0.5053 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0331 | 0.139 | 0.2455 |
Mycobacterium leprae | PROBABLE HYDROLASE | 0.0331 | 0.139 | 0.5 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0272 | 0.0614 | 0.2922 |
Onchocerca volvulus | Matrilysin homolog | 0.0603 | 0.4951 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0272 | 0.0614 | 0.1085 |
Schistosoma mansoni | hypothetical protein | 0.0385 | 0.2102 | 1 |
Mycobacterium ulcerans | hydrolase | 0.0331 | 0.139 | 0.5 |
Loa Loa (eye worm) | matrixin family protein | 0.0603 | 0.4951 | 0.8743 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Aggregation response (functional) | 0 | Compound was evaluated for aggregation properties on human platelets at 1.3 microM; Irreversible | ChEMBL. | 7086834 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.