Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Magnaporthe oryzae (strain 70-15 / FGSC 8958) (Rice blast fungus)(Pyricularia oryzae) | Scytalone dehydratase | Starlite/ChEMBL | References |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 6.4 nM | Compound was evaluated for its inhibition constant against scytalone dehydratase (SD) | ChEMBL. | 10743955 |
Ki (binding) | = 6.4 nM | Compound was evaluated for its inhibition constant against scytalone dehydratase (SD) | ChEMBL. | 10743955 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.