Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Cannabinoid CB1 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.161 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.0017 | 0.0017 |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0923 | 0.0017 | 0.0017 |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.161 | 1 | 1 |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.161 | 1 | 1 |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.0017 | 0.0017 |
Onchocerca volvulus | 0.161 | 1 | 1 | |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.161 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0923 | 0.0017 | 0.0017 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | nM | Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]-CP-55,940 as radioligand; not determined | ChEMBL. | 9876105 |
Ki (binding) | 0 nM | Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]-CP-55,940 as radioligand; not determined | ChEMBL. | 9876105 |
Ki (binding) | = 8090 nM | Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the absence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]-CP-55,940 as radioligand | ChEMBL. | 9876105 |
Ki (binding) | = 8090 nM | Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the absence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]-CP-55,940 as radioligand | ChEMBL. | 9876105 |
Ki (binding) | = 20000 nM | Binding affinity towards Cannabinoid receptor 2 from mouse spleen membranes using 0.8 nM [3H]-CP-55,940 as radioligand | ChEMBL. | 9876105 |
Ki (binding) | = 20000 nM | Binding affinity towards Cannabinoid receptor 2 from mouse spleen membranes using 0.8 nM [3H]-CP-55,940 as radioligand | ChEMBL. | 9876105 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.