Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.008 ug ml-1 | Compound was tested in vitro for antibacterial activity against Escherichia coli A-15119 | ChEMBL. | 2918506 |
MIC (functional) | = 0.008 ug ml-1 | Compound was tested in vitro for antibacterial activity against Escherichia coli A-15119 | ChEMBL. | 2918506 |
MIC (functional) | = 0.016 ug ml-1 | Compound was tested in vitro for antibacterial activity against Staphylococcus aureus, pen-res A-9606 | ChEMBL. | 2918506 |
MIC (functional) | = 0.016 ug ml-1 | Compound was tested in vitro for antibacterial activity against Enterobacter cloacae A-9695 | ChEMBL. | 2918506 |
MIC (functional) | = 0.03 ug ml-1 | Compound was tested in vitro for antibacterial activity against Serratia marcescens A-20019 | ChEMBL. | 2918506 |
MIC (functional) | = 0.03 ug ml-1 | Compound was tested in vitro for antibacterial activity against Proteus vulgaris A-21559 | ChEMBL. | 2918506 |
MIC (functional) | = 0.5 ug ml-1 | Compound was tested in vitro for antibacterial activity against Pseudomonas aeruginosa | ChEMBL. | 2918506 |
Relative rate (ADMET) | = 0.4 | Compound was evaluated for the rate of hydrolysis by renal dipeptidase relative to hog renal dipeptidase | ChEMBL. | 2918506 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.