Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.5951 | 0.5884 |
Echinococcus multilocularis | baculoviral IAP repeat containing protein | 0.0218 | 0.5951 | 0.5951 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0345 | 1 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0345 | 1 | 0.5 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0345 | 1 | 1 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0345 | 1 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0345 | 1 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0345 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0163 | 0.0163 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0345 | 1 | 1 |
Schistosoma mansoni | inhibitor of apoptosis (iap) domain family member | 0.0218 | 0.5951 | 0.5951 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0345 | 1 | 0.5 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0345 | 1 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0034 | 0.0105 | 0.0105 |
Echinococcus granulosus | baculoviral IAP repeat containing protein | 0.0218 | 0.5951 | 0.5951 |
Loa Loa (eye worm) | hypothetical protein | 0.0218 | 0.5951 | 0.5884 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0345 | 1 | 1 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0345 | 1 | 1 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0345 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0218 | 0.5951 | 0.5951 |
Onchocerca volvulus | Deterin homolog | 0.0218 | 0.5951 | 0.5884 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0034 | 0.0105 | 0.0105 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0345 | 1 | 0.5 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0036 | 0.0163 | 0.0163 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0345 | 1 | 1 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0345 | 1 | 0.5 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0345 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 1 | 1 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0036 | 0.0163 | 0.0163 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0218 | 0.5951 | 0.5884 |
Plasmodium vivax | RNA helicase-1, putative | 0.0345 | 1 | 1 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0345 | 1 | 1 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0345 | 1 | 0.5 |
Brugia malayi | Inhibitor of Apoptosis domain containing protein | 0.0218 | 0.5951 | 0.5884 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0345 | 1 | 0.5 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0345 | 1 | 1 |
Echinococcus multilocularis | inhibitor of apoptosis protein | 0.0218 | 0.5951 | 0.5951 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0034 | 0.0105 | 0.0105 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0345 | 1 | 1 |
Onchocerca volvulus | 0.0218 | 0.5951 | 0.5884 | |
Schistosoma mansoni | inhibitor of apoptosis protein | 0.0218 | 0.5951 | 0.5951 |
Echinococcus granulosus | inhibitor of apoptosis protein | 0.0218 | 0.5951 | 0.5951 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | 0 M | Inhibitory potency for alpha-glucosidase was determined at concentration up to 3.0 mM; No inhibition | ChEMBL. | 10340610 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.