Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nmda type glutamate receptor | 0.1278 | 1 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.077 | 0.32 | 0.32 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.077 | 0.32 | 0.32 |
Schistosoma mansoni | glutamate receptor NMDA | 0.12 | 0.895 | 0.5 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0669 | 0.1838 | 0.1838 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0669 | 0.1838 | 0.1838 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.061 | 0.105 | 0.105 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Remaining (binding) | = 39 % | Percent remaining of radioligand [3H]-CCPA binding to human adenosine A1 receptor at 10 uM | ChEMBL. | 14736246 |
Remaining (binding) | = 39 % | Percent remaining of radioligand [3H]-CCPA binding to human adenosine A1 receptor at 10 uM | ChEMBL. | 14736246 |
Remaining (binding) | = 86 % | Percent remaining of radioligand [3H]-DPCPX binding to human adenosine A1 receptor at 10 microM | ChEMBL. | 14736246 |
Remaining (binding) | = 86 % | Percent remaining of radioligand [3H]-DPCPX binding to human adenosine A1 receptor at 10 microM | ChEMBL. | 14736246 |
Remaining (binding) | = 101 % | Percent remaining of radioligand [3H]-DPCPX binding to human adenosine A1 receptor at 1 microM | ChEMBL. | 14736246 |
Remaining (binding) | = 101 % | Percent remaining of radioligand [3H]-DPCPX binding to human adenosine A1 receptor at 1 microM | ChEMBL. | 14736246 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.