Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0257 | 1 | 0.5 |
Giardia lamblia | Aldose reductase | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0257 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0257 | 1 | 0.5 |
Onchocerca volvulus | 0.0257 | 1 | 0.5 | |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Leishmania major | prostaglandin f2-alpha synthase/D-arabinose dehydrogenase | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0257 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Leishmania major | prostaglandin f synthase, putative | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0257 | 1 | 0.5 |
Leishmania major | aldo-keto reductase-like protein | 0.0257 | 1 | 0.5 |
Onchocerca volvulus | 0.0257 | 1 | 0.5 | |
Trypanosoma cruzi | aldo/keto reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0257 | 1 | 0.5 |
Mycobacterium ulcerans | oxidoreductase | 0.0257 | 1 | 0.5 |
Entamoeba histolytica | aldose reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0257 | 1 | 0.5 |
Trypanosoma brucei | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase | 0.0257 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Schistosoma mansoni | aldo-keto reductase | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | hypothetical protein | 0.0257 | 1 | 1 |
Entamoeba histolytica | aldose reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | dihydrodiol dehydrogenase, putative | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | oxidoreductase | 0.0257 | 1 | 0.5 |
Onchocerca volvulus | 0.0257 | 1 | 0.5 | |
Giardia lamblia | Aldose reductase | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0257 | 1 | 0.5 |
Onchocerca volvulus | 0.0257 | 1 | 0.5 | |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0257 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Trypanosoma cruzi | aldo-keto reductase | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Trichomonas vaginalis | aldo/keto reductase, putative | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Trypanosoma brucei | prostaglandin f synthase | 0.0257 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0257 | 1 | 1 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Onchocerca volvulus | 0.0257 | 1 | 0.5 | |
Leishmania major | aldehyde reductase, putative,oxidoreductase, putative | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Toxoplasma gondii | aldose reductase, putative | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Schistosoma mansoni | pol-related | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase | 0.0257 | 1 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 1 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0257 | 1 | 1 |
Brugia malayi | oxidoreductase, aldo/keto reductase family protein | 0.0257 | 1 | 0.5 |
Loa Loa (eye worm) | oxidoreductase | 0.0257 | 1 | 0.5 |
Trichomonas vaginalis | aldo-keto reductase, putative | 0.0257 | 1 | 0.5 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0257 | 1 | 1 |
Onchocerca volvulus | 0.0257 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 2 MU | Hallucinogenic activity i.e; ratio of effective dose of mescaline to the effective dose of the compound was determined in human | ChEMBL. | 2299636 |
Activity (functional) | = 2 MU | Hallucinogenic activity i.e; ratio of effective dose of mescaline to the effective dose of the compound was determined in human | ChEMBL. | 2299636 |
Log activity (functional) | = 0.301 | Log value of hallucinogenic activity was determined | ChEMBL. | 2299636 |
Relative activity (functional) | = 2 | Psychotomimetic potency of compound relative to that of mescaline (Human potency of mescaline = 1 MU) | ChEMBL. | 6737431 |
Relative activity (functional) | = 2 | Psychotomimetic potency of compound relative to that of mescaline (Human potency of mescaline = 1 MU) | ChEMBL. | 6737431 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.