Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | cannabinoid receptor 1 (brain) | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0019 | 0.5 | 0.5 | |
Echinococcus granulosus | Mastin | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Echinococcus multilocularis | enteropeptidase | 0.0019 | 0.5 | 0.5 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0019 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0019 | 0.5 | 0.5 | |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0019 | 0.5 | 0.5 |
Echinococcus granulosus | enteropeptidase | 0.0019 | 0.5 | 0.5 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Brugia malayi | Trypsin family protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0019 | 0.5 | 0.5 | |
Echinococcus multilocularis | Mastin | 0.0019 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0019 | 0.5 | 0.5 | |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0019 | 0.5 | 0.5 |
Brugia malayi | Trypsin family protein | 0.0019 | 0.5 | 0.5 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0019 | 0.5 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.5 | 0.5 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0019 | 0.5 | 0.5 |
Loa Loa (eye worm) | trypsin family protein | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0019 | 0.5 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0019 | 0.5 | 0.5 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0019 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0019 | 0.5 | 0.5 | |
Brugia malayi | Trypsin family protein | 0.0019 | 0.5 | 0.5 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0019 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.