Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.1553 | 0.5902 | 0.5902 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.2516 | 1 | 1 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.2516 | 1 | 1 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.2516 | 1 | 1 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.1553 | 0.5902 | 0.5 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.2516 | 1 | 1 |
Leishmania major | C-8 sterol isomerase-like protein | 0.1553 | 0.5902 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0794 | 0.2671 | 0.2671 |
Brugia malayi | ERG2 and Sigma1 receptor like protein | 0.1553 | 0.5902 | 0.5902 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0166 | 0 | 0.5 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.1553 | 0.5902 | 0.5 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.2516 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Sweetness potency (binding) | 0 | Compound was evaluated for sweetness potency at 1 mg/mL sucrose solution ; weakly bitter | ChEMBL. | 1542101 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.