Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.2171 | 0 | 0.5 |
Onchocerca volvulus | 0.2492 | 1 | 0.5 | |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.2171 | 0 | 0.5 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.2171 | 0 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.2492 | 1 | 1 |
Onchocerca volvulus | 0.2492 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
KD app (functional) | = 560 uM | Compound was tested for agonistic activity at the N-methyl-D-aspartate glutamate receptor obtained from the rat cortical wedge preparation | ChEMBL. | 10782683 |
KD app (functional) | = 560 uM | Compound was tested for agonistic activity at the N-methyl-D-aspartate glutamate receptor obtained from the rat cortical wedge preparation | ChEMBL. | 10782683 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.