% of selectivity (functional)
|
= 0 %
|
Percent selectivity of the compound was evaluated in breast BT-549 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 0 %
|
Percent selectivity of the compound was evaluated in breast BT-549 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 17 %
|
Percent selectivity of the compound was evaluated in leukaemia HL-60(TB) cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 17 %
|
Percent selectivity of the compound was evaluated in ovarian IGROV1 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 17 %
|
Percent selectivity of the compound was evaluated in leukaemia HL-60(TB) cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 17 %
|
Percent selectivity of the compound was evaluated in ovarian IGROV1 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 25 %
|
Percent selectivity of the compound was evaluated in NSCL H-522 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 33 %
|
Percent selectivity of the compound was evaluated in CNS SNB-75 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 33 %
|
Percent selectivity of the compound was evaluated in CNS SNB-75 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 50 %
|
Percent selectivity of the compound was evaluated in prostrate PC-3 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 50 %
|
Percent selectivity of the compound was evaluated in prostrate PC-3 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 57 %
|
Percent selectivity of the compound was evaluated in colon HCC-2998 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 57 %
|
Percent selectivity of the compound was evaluated in colon HCC-2998 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 87 %
|
Percent selectivity of the compound was evaluated in melanoma SK-MEL-5 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 87 %
|
Percent selectivity of the compound was evaluated in melanoma SK-MEL-5 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 100 %
|
Percent selectivity of the compound was evaluated in renal RXF-393 cell lines
|
ChEMBL.
|
11312925
|
% of selectivity (functional)
|
= 100 %
|
Percent selectivity of the compound was evaluated in renal RXF-393 cell lines
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic Activity against cultured cells of P-388 murine leukemia.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic activity against cultured cells of A-549 human lung carcinoma.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic activity against cultured cells of HT-29 human colon carcinoma.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic activity against cultured cells of MEL-28 malign human melanoma.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic Activity against cultured cells of P-388 murine leukemia.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic activity against cultured cells of A-549 human lung carcinoma.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic activity against cultured cells of HT-29 human colon carcinoma.
|
ChEMBL.
|
11312925
|
IC50 (functional)
|
= 0.2 uM
|
Cytotoxic activity against cultured cells of MEL-28 malign human melanoma.
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 2.75 uM
|
Concentration required for killing 50% of cells of renal RXF-393 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 2.75 uM
|
Concentration required for killing 50% of cells of renal RXF-393 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 3.55 uM
|
Concentration required for killing 50% of cells of colon HCC-2998 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 3.55 uM
|
Concentration required for killing 50% of cells of colon HCC-2998 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 4.53 uM
|
Concentration required for killing 50% of cells of melanoma SK-MEL-5 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 4.53 uM
|
Concentration required for killing 50% of cells of melanoma SK-MEL-5 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 4.92 uM
|
Concentration required for killing 50% of the NSCL H-522 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 7.32 uM
|
Concentration required for killing 50% of cells of prostrate PC-3 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 7.32 uM
|
Concentration required for killing 50% of cells of prostrate PC-3 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 7.59 uM
|
Concentration required for killing 50% of cells of leukaemia HL-60(TB) cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 7.59 uM
|
Concentration required for killing 50% of cells of leukaemia HL-60(TB) cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 8.71 uM
|
Concentration required for killing 50% of cells of ovarian IGROV1 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 8.71 uM
|
Concentration required for killing 50% of cells of ovarian IGROV1 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 9.64 uM
|
Concentration required for killing 50% of cells of CNS SNB-75 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 9.64 uM
|
Concentration required for killing 50% of cells of CNS SNB-75 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 22.4 uM
|
Concentration required for killing 50% of cells of breast BT-549 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|
LC50 (functional)
|
= 22.4 uM
|
Concentration required for killing 50% of cells of breast BT-549 cell lines was determined in vitro
|
ChEMBL.
|
11312925
|