Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nmda type glutamate receptor | 0.0536 | 1 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.042 | 0.7127 | 0.1439 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.048 | 0.8623 | 0.5 |
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.0524 | 0.9712 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0524 | 0.9712 | 0.5 |
Schistosoma mansoni | d-amino acid oxidase | 0.0524 | 0.9712 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.042 | 0.7127 | 0.7127 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0401 | 0.6645 | 0.6645 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0524 | 0.9712 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.008 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. pyogenes EES61 using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | = 0.008 ug ml-1 | In vitro minimum inhibitory concentration against S. pneumoniae ATCC6303. | ChEMBL. | 10782693 |
MIC (functional) | = 0.2 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. aureus 6538P using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | = 3.1 ug ml-1 | In vitro minimum inhibitory concentration against S. aureus A5177. | ChEMBL. | 10782693 |
MIC (functional) | = 4 ug ml-1 | In vitro minimum inhibitory concentration of the compound against Haemophilus influenzae DILL using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | = 16 ug ml-1 | In vitro minimum inhibitory concentration against S. pneumoniae 5649. | ChEMBL. | 10782693 |
MIC (functional) | = 32 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. pyogenes PIU 2548 using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | = 128 ug ml-1 | In vitro minimum inhibitory concentration of the compound against S. pyogenes 930 using standard agar dilution method | ChEMBL. | 10782693 |
MIC (functional) | = 128 ug ml-1 | In vitro minimum inhibitory concentration against S. pneumoniae 5737. | ChEMBL. | 10782693 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.