Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Histone deacetylase family protein | 0.0053 | 0.0178 | 1 |
Entamoeba histolytica | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0523 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0257 | 0.3412 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0053 | 0.0178 | 1 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0257 | 0.3412 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0041 | 0 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Plasmodium falciparum | histone deacetylase 2 | 0.0053 | 0.0178 | 0.0178 |
Echinococcus granulosus | histone deacetylase 6 | 0.0053 | 0.0178 | 1 |
Plasmodium falciparum | peptide deformylase | 0.0674 | 1 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0053 | 0.0178 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0053 | 0.0178 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Plasmodium vivax | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0178 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0053 | 0.0178 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0257 | 0.3412 | 1 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0053 | 0.0178 | 1 |
Giardia lamblia | Histone deacetylase | 0.0041 | 0 | 0.5 |
Plasmodium falciparum | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0178 |
Trypanosoma brucei | histone deacetylase 4 | 0.0053 | 0.0178 | 0.0523 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0053 | 0.0178 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0523 |
Leishmania major | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0523 |
Toxoplasma gondii | hypothetical protein | 0.0674 | 1 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0053 | 0.0178 | 0.0178 |
Echinococcus multilocularis | histone deacetylase | 0.0053 | 0.0178 | 1 |
Trypanosoma brucei | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0523 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0053 | 0.0178 | 1 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0053 | 0.0178 | 1 |
Brugia malayi | Histone deacetylase family protein | 0.0053 | 0.0178 | 1 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0674 | 1 | 0.5 |
Trypanosoma brucei | histone deacetylase 3 | 0.0053 | 0.0178 | 0.0523 |
Loa Loa (eye worm) | histone deacetylase | 0.0053 | 0.0178 | 1 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0257 | 0.3412 | 1 |
Leishmania major | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0523 |
Echinococcus granulosus | histone deacetylase 6 | 0.0053 | 0.0178 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0041 | 0 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.0674 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0053 | 0.0178 | 0.0523 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0053 | 0.0178 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0053 | 0.0178 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0053 | 0.0178 | 0.0178 |
Echinococcus granulosus | histone deacetylase 6 | 0.0053 | 0.0178 | 1 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0257 | 0.3412 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0257 | 0.3412 | 1 |
Trichomonas vaginalis | histone deacetylase 1, 2 ,3, putative | 0.0041 | 0 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0257 | 0.3412 | 1 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0674 | 1 | 0.5 |
Trichomonas vaginalis | histone deacetylase, putative | 0.0041 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0674 | 1 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.0674 | 1 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.0674 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.