Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | glutamate receptor NMDA | 0.033 | 0.8584 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1821 | 0.5 |
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.0166 | 0.1821 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0365 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0243 | 0.5003 | 0.5003 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.0152 | 0.1252 | 0.5 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0265 | 0.5915 | 0.1825 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0166 | 0.1821 | 0.5 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0265 | 0.5915 | 0.5915 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
TOC ED50 (functional) | NA 0 M | Compound is evaluated for its intrinsic ability to control epithelial cell diferentiation by retinoids in hamster tracheal organ culture at 10e-9 M ;IA = inactive(3/4) 3 were inactive out of 4 | ChEMBL. | 7401108 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.