Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE D-AMINO ACID OXIDASE AAO | 0.0162 | 1 | 0.5 |
Schistosoma mansoni | d-amino acid oxidase | 0.0162 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0106 | 0.5863 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0083 | 0.4179 | 0.1439 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0083 | 0.4179 | 0.7127 |
Mycobacterium ulcerans | D-amino acid oxidase Aao | 0.0162 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable D-amino acid oxidase Aao | 0.0148 | 0.9002 | 0.5 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0106 | 0.5863 | 1 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0079 | 0.3896 | 0.6645 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 15 % | In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits at 1 microM | ChEMBL. | 8145231 |
Inhibition (binding) | = 15 % | In vitro inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in liver microsomes isolated from cholesterol-fed rabbits at 1 microM | ChEMBL. | 8145231 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.