Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 1 | 1 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0086 | 1 | 1 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0086 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 1 | 1 | |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0086 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 1 | 1 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0086 | 1 | 1 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0086 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0086 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Echinococcus granulosus | enteropeptidase | 0.0086 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Loa Loa (eye worm) | trypsin family protein | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0086 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 1 | 1 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0086 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0086 | 1 | 0.5 |
Onchocerca volvulus | 0.0086 | 1 | 1 | |
Echinococcus multilocularis | enteropeptidase | 0.0086 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Echinococcus granulosus | Mastin | 0.0086 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 1 | 1 | |
Brugia malayi | Trypsin family protein | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0086 | 1 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0086 | 1 | 1 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0086 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0086 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 1 | 0.5 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0086 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0086 | 1 | 1 |
Echinococcus multilocularis | Mastin | 0.0086 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0086 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI (functional) | = 54 % | Percentage growth inhibition of Toxoplasma gondii at concentration of 2 microg/mL using an human myelomonocytic cell line THP-1 | ChEMBL. | 10853649 |
GI (functional) | = 54 % | Percentage growth inhibition of Toxoplasma gondii at concentration of 2 microg/mL using an human myelomonocytic cell line THP-1 | ChEMBL. | 10853649 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.