Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | kinesin family 1 | 0.0202 | 0.6042 | 0.5 |
Trypanosoma brucei | RNA helicase, putative | 0.0318 | 1 | 0.5 |
Brugia malayi | Kinesin motor domain containing protein | 0.0026 | 0 | 0.5 |
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0026 | 0 | 0.5 |
Plasmodium falciparum | kinesin-5 | 0.0026 | 0 | 0.5 |
Entamoeba histolytica | kinesin, putative | 0.0026 | 0 | 0.5 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0026 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0176 | 0.514 | 0.514 |
Plasmodium vivax | kinesin-5 | 0.0026 | 0 | 0.5 |
Echinococcus multilocularis | kinesin family 1 | 0.0202 | 0.6042 | 0.5 |
Giardia lamblia | Kinesin-5 | 0.0026 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.