Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED20 (functional) | = 0.081 mM kg-1 | Hypoglycemic activity by lowering blood glucose in normal rats by 20% after oral administration. | ChEMBL. | 6864736 |
ED50 (functional) | = 0.19 mM kg-1 | Hypoglycemic activity by lowering blood glucose in normal rats by 50% after oral administration. | ChEMBL. | 6864736 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.