Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0575 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0575 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0575 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0575 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0575 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0575 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0575 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0575 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 21.1 uM | Inhibitory concentration of thecompound was determined againstmelanoma B16 cells | ChEMBL. | 15634028 |
IC50 (functional) | = 21.1 uM | Inhibitory concentration of thecompound was determined againstmelanoma B16 cells | ChEMBL. | 15634028 |
IC50 (functional) | = 40.3 uM | Inhibitory concentration of thecompound was determined againstmelanocyte Mel-A cells | ChEMBL. | 15634028 |
IC50 (functional) | = 40.3 uM | Inhibitory concentration of thecompound was determined againstmelanocyte Mel-A cells | ChEMBL. | 15634028 |
IC50 (functional) | = 41.6 uM | Inhibitory concentration of thecompound was determined against L1210 cells | ChEMBL. | 15634028 |
IC50 (functional) | = 41.6 uM | Inhibitory concentration of thecompound was determined against L1210 cells | ChEMBL. | 15634028 |
IC50 (binding) | = 350 uM | Inhibitory concentration against 20S proteasome chymotrypsin-like activity | ChEMBL. | 15634028 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.