Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0466 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0466 | 0.5 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0466 | 0.5 | 0.5 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0466 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0466 | 0.5 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0466 | 0.5 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0466 | 0.5 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0466 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 9 nM | Inhibitory concentration of thecompound against Escherichia coliwas determined | ChEMBL. | 15686939 |
IC50 (functional) | = 9 nM | Inhibitory concentration of thecompound against Escherichia coliwas determined | ChEMBL. | 15686939 |
IC50 (functional) | = 75 nM | Inhibitory concentration of thecompound against Staphylococcusaureus was determined | ChEMBL. | 15686939 |
MIC (functional) | = 2 ug ml-1 | Minimum inhibitory concentrationof the compound againstEscherichia coli HN818 strain wasdetermined | ChEMBL. | 15686939 |
MIC (functional) | = 2 ug ml-1 | Minimum inhibitory concentrationof the compound againstEscherichia coli HN818 strain wasdetermined | ChEMBL. | 15686939 |
MIC (functional) | = 8 ug ml-1 | Minimum inhibitory concentrationof the compound againstStaphylococcus aureus 133 strainwas determined | ChEMBL. | 15686939 |
MIC (functional) | = 32 ug ml-1 | Minimum inhibitory concentrationof the compound againstEscherichia coli Neumann strainwas determined | ChEMBL. | 15686939 |
MIC (functional) | = 32 ug ml-1 | Minimum inhibitory concentrationof the compound againstEscherichia coli Neumann strainwas determined | ChEMBL. | 15686939 |
MIC (functional) | = 323 ug ml-1 | Minimum inhibitory concentration of the compound against Streptococcus pneumoniae G9A strain was determined | ChEMBL. | 15686939 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Escherichia coli | ChEMBL23 | 15686939 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.