Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | glutamate receptor NMDA | 0.0078 | 0.1376 | 0.1521 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.015 | 0.9045 | 1 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.008 | 0.159 | 0.1758 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.008 | 0.159 | 0.1758 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0066 | 0 | 0.5 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0066 | 0 | 0.5 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0093 | 0.2966 | 0.3279 |
Echinococcus granulosus | glutamate receptor 2 | 0.008 | 0.159 | 0.1758 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0093 | 0.2966 | 0.3279 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.008 | 0.159 | 0.1758 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0078 | 0.1376 | 0.1521 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.008 | 0.159 | 0.1758 |
Echinococcus granulosus | nmda type glutamate receptor | 0.015 | 0.9045 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.008 | 0.159 | 0.1758 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.008 | 0.159 | 0.1758 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.008 | 0.159 | 0.1758 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0066 | 0 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0072 | 0.0635 | 0.0702 |
Echinococcus multilocularis | glutamate receptor 2 | 0.008 | 0.159 | 0.1758 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.008 | 0.159 | 0.1758 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 14 % | Inhibitory concentration against leukocyte function-associated antigen-1 in the adhesion of the HSB-2 human lymphoblast cell line to H1HeLa cells | ChEMBL. | 15686933 |
Inhibition (functional) | = 14 % | Inhibitory concentration against leukocyte function-associated antigen-1 in the adhesion of the HSB-2 human lymphoblast cell line to H1HeLa cells | ChEMBL. | 15686933 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.