Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0221 | 1 | 1 |
Loa Loa (eye worm) | LBP/BPI/CETP family domain-containing protein | 0.0221 | 1 | 1 |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Brugia malayi | LBP / BPI / CETP family, N-terminal domain containing protein | 0.0221 | 1 | 1 |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Onchocerca volvulus | 0.0221 | 1 | 1 | |
Brugia malayi | LBP / BPI / CETP family, C-terminal domain containing protein | 0.0221 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 6 ug ml-1 | Minimum inhibitory concentration required for antibacterial activity against Staphylococcus aureus ATCC 2943; gram positive | ChEMBL. | 15261267 |
MIC (functional) | = 8 ug ml-1 | Minimum inhibitory concentration required for antibacterial activity against Bacillus subtilis ATCC 6633; gram positive | ChEMBL. | 15261267 |
MIC (functional) | = 10 ug ml-1 | Minimum inhibitory concentration required for antibacterial activity against Escherichia coli ATCC 13607; gram negative | ChEMBL. | 15261267 |
MIC (functional) | = 10 ug ml-1 | Minimum inhibitory concentration required for antibacterial activity against Escherichia coli ATCC 13607; gram negative | ChEMBL. | 15261267 |
MIC (functional) | = 13 ug ml-1 | Minimum inhibitory concentration required for antibacterial activity against Pseudomonas diminuta MTCC 3361; gram negative | ChEMBL. | 15261267 |
MIC (functional) | = 20 ug ml-1 | Minimum inhibitory concentration required for antifungal activity against Candida albicans ATCC 10321 | ChEMBL. | 15261267 |
MIC (functional) | = 20 ug ml-1 | Minimum inhibitory concentration required for antifungal activity against Candida albicans ATCC 10321 | ChEMBL. | 15261267 |
MIC (functional) | = 24 ug ml-1 | Minimum inhibitory concentration required for antifungal activity against Aspergillus niger ATCC 16404 | ChEMBL. | 15261267 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.