Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Kinase, CMGC CDK | 0.0576 | 0 | 0.5 |
Plasmodium vivax | protein kinase Crk2 | 0.0576 | 0 | 0.5 |
Loa Loa (eye worm) | camk/mapkapk/mapkapk protein kinase | 0.2578 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0576 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0576 | 0 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0576 | 0 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0576 | 0 | 0.5 |
Echinococcus granulosus | MAP kinase activated protein kinase 2 | 0.2578 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.2578 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0576 | 0 | 0.5 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0576 | 0 | 0.5 |
Plasmodium falciparum | protein kinase 5 | 0.0576 | 0 | 0.5 |
Leishmania major | cell division related protein kinase 2,cdc2-related kinase | 0.0576 | 0 | 0.5 |
Leishmania major | cell division protein kinase 2,cdc2-related kinase | 0.0576 | 0 | 0.5 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0576 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0576 | 0 | 0.5 |
Echinococcus multilocularis | MAP kinase activated protein kinase 2 | 0.2578 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0576 | 0 | 0.5 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0576 | 0 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0576 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0576 | 0 | 0.5 |
Giardia lamblia | Kinase, CMGC CDK | 0.0576 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
pka (ADMET) | = 4.68 | Acidity of the compound determined sphectrometrically | ChEMBL. | 7310804 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.