Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | melanin-concentrating hormone receptor 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Cytidine deaminase | 0.011 | 1 | 1 |
Echinococcus multilocularis | cytidine deaminase | 0.011 | 1 | 1 |
Mycobacterium leprae | PROBABLE CYTIDINE DEAMINASE CDD (CYTIDINE AMINOHYDROLASE) (CYTIDINE NUCLEOSIDE DEAMINASE) | 0.011 | 1 | 0.5 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0024 | 0.0212 | 0.0212 |
Leishmania major | cytidine deaminase-like protein | 0.011 | 1 | 1 |
Trypanosoma cruzi | cytidine deaminase-like protein | 0.011 | 1 | 1 |
Mycobacterium tuberculosis | Probable cytidine deaminase Cdd (cytidine aminohydrolase) (cytidine nucleoside deaminase) | 0.011 | 1 | 0.5 |
Trypanosoma brucei | ingi protein (ORF1) | 0.0024 | 0.0212 | 0.0212 |
Onchocerca volvulus | 0.011 | 1 | 1 | |
Entamoeba histolytica | cytidine deaminase, putative | 0.011 | 1 | 0.5 |
Trypanosoma brucei | retrotransposon hot spot protein 4 (RHS4), interrupted | 0.0024 | 0.0212 | 0.0212 |
Trypanosoma brucei | cytidine deaminase | 0.011 | 1 | 1 |
Toxoplasma gondii | cytidine and deoxycytidylate deaminase zinc-binding region domain-containing protein | 0.011 | 1 | 1 |
Trypanosoma brucei | RNA helicase, putative | 0.0082 | 0.6869 | 0.6869 |
Trypanosoma cruzi | cytidine deaminase-like protein, putative | 0.011 | 1 | 1 |
Treponema pallidum | ribonuclease H (rnhA) | 0.0022 | 0 | 0.5 |
Trypanosoma brucei | unspecified product | 0.0024 | 0.0212 | 0.0212 |
Mycobacterium ulcerans | cytidine deaminase | 0.011 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 0.6869 | 1 |
Onchocerca volvulus | 0.011 | 1 | 1 | |
Wolbachia endosymbiont of Brugia malayi | ribonuclease HI | 0.0022 | 0 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0.0212 | 0.0212 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.011 | 1 | 1 |
Echinococcus granulosus | cytidine deaminase | 0.011 | 1 | 1 |
Trichomonas vaginalis | cytidine deaminase, putative | 0.011 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 61 nM | Binding affinity towards the human MCH-R1 receptor by displacing [125I]-Tyr13]-MCH radioligand in HEK293 cells, Data is average of 3 or more independent measurements | ChEMBL. | 15950467 |
Ki (binding) | = 61 nM | Binding affinity towards the human MCH-R1 receptor by displacing [125I]-Tyr13]-MCH radioligand in HEK293 cells, Data is average of 3 or more independent measurements | ChEMBL. | 15950467 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.