Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | nmda type glutamate receptor | 0.0497 | 0.5 | 0.5 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0497 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC100 (binding) | = 5 uM | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
IC100 (binding) | = 5 uM | Inhibition of NFkappaB DNA binding by EMSA | ChEMBL. | 16570920 |
IC100 (binding) | = 5 uM | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
IC100 (binding) | = 5 uM | Inhibition of NFkappaB DNA binding by EMSA | ChEMBL. | 16570920 |
pIC100 (binding) | = -0.69 | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
pIC100 (binding) | = -0.69 | Concentration required for complete inhibition of Nuclear factor kappa B DNA binding | ChEMBL. | 15537359 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.