Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | Starlite/ChEMBL | References |
Species | Potential target | Known druggable target/s | Ortholog Group |
---|---|---|---|
Echinococcus multilocularis | integrin beta 2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Echinococcus granulosus | integrin beta 2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | Integrin beta-3 precursor, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Brugia malayi | Integrin beta pat-3 precursor | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma mansoni | integrin beta subunit | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | Integrin beta-PS precursor, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Loa Loa (eye worm) | integrin beta-2 | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Schistosoma japonicum | ko:K06464 integrin beta 2, putative | Get druggable targets OG5_127959 | All targets in OG5_127959 |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | Glycosyl transferase family 35 | 0.1938 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1938 | 1 | 1 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0838 | 0.3586 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.1938 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0838 | 0.3586 | 0.3586 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1938 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.1938 | 1 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.1938 | 1 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.1938 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.1938 | 1 | 1 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.1938 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1938 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.1938 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0838 | 0.3586 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.1938 | 1 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.1938 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.1938 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.1938 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.1938 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.