Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0332 | 0.4688 | 0.4688 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0332 | 0.4688 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0332 | 0.4688 | 0.4688 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0332 | 0.4688 | 0.4688 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0332 | 0.4688 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0332 | 0.4688 | 0.4688 |
Schistosoma mansoni | glycogen phosphorylase | 0.0332 | 0.4688 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0332 | 0.4688 | 1 |
Giardia lamblia | Glycogen phosphorylase | 0.0332 | 0.4688 | 0.5 |
Echinococcus multilocularis | geminin | 0.0171 | 0.0526 | 0.0526 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0332 | 0.4688 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.0332 | 0.4688 | 0.4688 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0332 | 0.4688 | 0.5 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0332 | 0.4688 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0332 | 0.4688 | 0.4688 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0536 | 1 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0332 | 0.4688 | 1 |
Echinococcus granulosus | geminin | 0.0171 | 0.0526 | 0.0526 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0332 | 0.4688 | 0.5 |
Brugia malayi | carbohydrate phosphorylase | 0.0332 | 0.4688 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | NT 0 % | Inhibition of histamine release from sensitized guinea pig chopped lung, upon antigen challenge at 10 ug/mL. | ChEMBL. | 3612683 |
Inhibition (functional) | = 21 % | Inhibition of slow reacting substance of anaphylaxis (SRS-A) release from sensitized guinea pig chopped lung upon antigen challenge at 10 ug/mL | ChEMBL. | 3612683 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.