Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 16.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 8.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 4.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 64.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | ChEMBL. | 16040241 | |
MIC (functional) | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 32.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 | |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 4.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 8.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 16.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 32.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | - 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 64.0 uM/ml in dimethylformamide, - = susceptible | ChEMBL. | 16040241 |
MIC (functional) | - 0 | Antibacterial activity against Pseudomonas aeruginosa (ATCC 27853) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 0.5 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 1.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 4.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 8.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 16.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 32.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 64.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | - 0 | Antibacterial activity against Staphylococcus aureus (ATCC 25923) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 2.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 4.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 8.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 16.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 32.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 64.0 uM/ml in dimethylformamide, + = resistant | ChEMBL. | 16040241 |
MIC (functional) | - 0 | Antibacterial activity against Escherichia coli (ATCC 25922) at concentration 128.0 uM/ml in dimethylformamide, - = susceptible | ChEMBL. | 16040241 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.