Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | dynamin 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.092 | 0.0286 |
Trypanosoma brucei | dynamin-1-like protein | 0.0026 | 0.0653 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0026 | 0.0653 | 0.5 |
Trypanosoma brucei | dynamin-1-like protein | 0.0026 | 0.0653 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0243 | 0.8554 | 0.8453 |
Trichomonas vaginalis | dynamin, putative | 0.0026 | 0.0653 | 0.5 |
Trichomonas vaginalis | interferon-induced GTP-binding protein mx, putative | 0.0026 | 0.0653 | 0.5 |
Echinococcus granulosus | dynamin 1 | 0.0028 | 0.0725 | 0.0699 |
Trichomonas vaginalis | dynamin, putative | 0.0026 | 0.0653 | 0.5 |
Echinococcus granulosus | MAM | 0.0033 | 0.092 | 0.0895 |
Echinococcus granulosus | dynamin 1 protein | 0.0026 | 0.0653 | 0.0627 |
Echinococcus multilocularis | dynamin | 0.0026 | 0.0653 | 0.0627 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.092 | 0.0286 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0725 | 0.0077 |
Plasmodium vivax | dynamin protein, putative | 0.0026 | 0.0653 | 0.5 |
Schistosoma mansoni | dynamin | 0.0028 | 0.0725 | 0.7813 |
Plasmodium falciparum | dynamin-like protein | 0.0026 | 0.0653 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0026 | 0.0653 | 0.5 |
Echinococcus multilocularis | tyrosine protein kinase | 0.0283 | 1 | 1 |
Toxoplasma gondii | dynamin-related protein DRPB | 0.0026 | 0.0653 | 1 |
Trichomonas vaginalis | mgm1, putative | 0.0026 | 0.0653 | 0.5 |
Brugia malayi | Dynamin | 0.0028 | 0.0725 | 0.0077 |
Echinococcus multilocularis | dynamin 1 protein | 0.0026 | 0.0653 | 0.0627 |
Echinococcus granulosus | dynamin | 0.0026 | 0.0653 | 0.0627 |
Brugia malayi | Dynamin | 0.0028 | 0.0725 | 0.0077 |
Entamoeba histolytica | dynamin-like protein | 0.0026 | 0.0653 | 1 |
Leishmania major | GTP-binding protein, putative | 0.0026 | 0.0653 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0026 | 0.0653 | 0.5 |
Plasmodium vivax | dynamin-like protein, putative | 0.0026 | 0.0653 | 0.5 |
Echinococcus granulosus | tyrosine protein kinase | 0.0283 | 1 | 1 |
Entamoeba histolytica | dynamin-1-like protein, putative | 0.0026 | 0.0653 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0279 | 0.9865 | 0.9856 |
Trypanosoma cruzi | dynamin-1-like protein | 0.0026 | 0.0653 | 0.5 |
Schistosoma mansoni | dynamin | 0.0028 | 0.0725 | 0.7813 |
Toxoplasma gondii | dynamin-related protein DRPA | 0.0026 | 0.0653 | 1 |
Giardia lamblia | Dynamin | 0.0026 | 0.0653 | 0.5 |
Trichomonas vaginalis | dynamin, putative | 0.0026 | 0.0653 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.092 | 1 |
Echinococcus multilocularis | dynamin 1 | 0.0028 | 0.0725 | 0.0699 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.092 | 0.0286 |
Brugia malayi | hypothetical protein | 0.0033 | 0.092 | 0.0286 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.092 | 1 |
Plasmodium falciparum | dynamin-like protein | 0.0026 | 0.0653 | 0.5 |
Schistosoma mansoni | dynamin | 0.0026 | 0.0653 | 0.7007 |
Echinococcus multilocularis | MAM | 0.0033 | 0.092 | 0.0895 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0279 | 0.9862 | 0.9852 |
Loa Loa (eye worm) | hypothetical protein | 0.028 | 0.9895 | 0.9887 |
Loa Loa (eye worm) | TK protein kinase | 0.0283 | 1 | 1 |
Onchocerca volvulus | 0.0039 | 0.1124 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.