Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 3.05 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 3.05 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 3.05 ug ml-1 | Antimalarial activity against chloroquine-resistant Plasmodium falciparum FLD-NG assessed as inhibition of schizont maturation | ChEMBL. | 22632793 |
IC50 (functional) | = 5.75 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 5.75 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 18 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 18 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 18 ug ml-1 | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum FLD-B assessed as inhibition of schizont maturation | ChEMBL. | 22632793 |
IC50 (functional) | = 28.5 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC50 (functional) | = 28.5 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 7 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 7 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 27.5 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 27.5 ug ml-1 | Anti-malarial activity against chloroquine resistant Plasmodium falciparum FDL-NG for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 32 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 32 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for schizont maturation inhibition after 24 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 115 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
IC90 (functional) | = 115 ug ml-1 | Anti-malarial activity against chloroquine sensitive Plasmodium falciparum FDL-B for total parasite growth inhibition after 48 hrs | ChEMBL. | 16213708 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Plasmodium falciparum | ChEMBL23 | 16213708 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.