Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | FtsZ inactivation in MTB cells at MIC | ChEMBL. | 16420032 | |
Activity (binding) | NA 0 | FtsZ inactivation in MTB cells at MIC | ChEMBL. | 16420032 |
IC50 (functional) | NA 0 | Cytotoxicity against human MCF7 cell line | ChEMBL. | 16420032 |
IC50 (functional) | NA 0 | Cytotoxicity against human A549 cell line | ChEMBL. | 16420032 |
MIC99 (functional) | Antimicrobial activity against Mycobacterium tuberculosis H37Rv | ChEMBL. | 16420032 | |
MIC99 (functional) | Antimicrobial activity against Mycobacterium tuberculosis IMCJ946.K2 | ChEMBL. | 16420032 | |
MIC99 (functional) | NA 0 | Antimicrobial activity against Mycobacterium tuberculosis H37Rv | ChEMBL. | 16420032 |
MIC99 (functional) | NA 0 | Antimicrobial activity against Mycobacterium tuberculosis IMCJ946.K2 | ChEMBL. | 16420032 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.