Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | malic enzyme 1, NADP(+)-dependent, cytosolic | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | malic enzyme, putative | 0.0014 | 1 | 1 |
Schistosoma mansoni | malic enzyme | 0.0014 | 1 | 1 |
Entamoeba histolytica | malic enzyme, putative | 0.0007 | 0 | 0.5 |
Trichomonas vaginalis | malic enzyme, putative | 0.0014 | 1 | 1 |
Mycobacterium tuberculosis | Probable [NAD] dependent malate oxidoreductase Mez (malic enzyme) (NAD-malic enzyme) (malate dehydrogenase (oxaloacetate decarbo | 0.0014 | 1 | 0.5 |
Leishmania major | malic enzyme, putative | 0.0014 | 1 | 0.5 |
Echinococcus multilocularis | NADP dependent malic enzyme | 0.0014 | 1 | 0.5 |
Trichomonas vaginalis | malic enzyme, putative | 0.0014 | 1 | 1 |
Trypanosoma cruzi | malic enzyme, putative | 0.0014 | 1 | 0.5 |
Trichomonas vaginalis | malic enzyme, putative | 0.0014 | 1 | 1 |
Entamoeba histolytica | malic enzyme, putative | 0.0007 | 0 | 0.5 |
Trichomonas vaginalis | malic enzyme, putative | 0.001 | 0.4684 | 0.4684 |
Mycobacterium ulcerans | malate dehydrogenase | 0.0014 | 1 | 1 |
Brugia malayi | NAD-dependent malic enzyme, mitochondrial precursor, putative | 0.0014 | 1 | 1 |
Onchocerca volvulus | Malic enzyme homolog | 0.0014 | 1 | 0.5 |
Onchocerca volvulus | Malic enzyme homolog | 0.0014 | 1 | 0.5 |
Trypanosoma cruzi | malic enzyme | 0.0014 | 1 | 0.5 |
Echinococcus granulosus | NADP dependent malic enzyme | 0.0014 | 1 | 0.5 |
Giardia lamblia | Malic enzyme | 0.0014 | 1 | 0.5 |
Trypanosoma cruzi | malic enzyme | 0.0014 | 1 | 0.5 |
Trypanosoma brucei | NADP-dependent malic enzyme, cytosolic | 0.0014 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | malic enzyme | 0.0007 | 0 | 0.5 |
Loa Loa (eye worm) | NADP-malic enzyme | 0.001 | 0.4684 | 0.5 |
Trypanosoma brucei | malic enzyme | 0.0014 | 1 | 0.5 |
Onchocerca volvulus | Malic enzyme homolog | 0.0014 | 1 | 0.5 |
Trichomonas vaginalis | malic enzyme, putative | 0.0014 | 1 | 1 |
Trypanosoma cruzi | malic enzyme, putative | 0.0014 | 1 | 0.5 |
Echinococcus multilocularis | NADP dependent malic enzyme | 0.0014 | 1 | 0.5 |
Echinococcus multilocularis | NADP dependent malic enzyme | 0.0014 | 1 | 0.5 |
Echinococcus granulosus | NADP dependent malic enzyme | 0.0014 | 1 | 0.5 |
Echinococcus granulosus | NADP dependent malic enzyme | 0.0014 | 1 | 0.5 |
Onchocerca volvulus | Malic enzyme homolog | 0.0014 | 1 | 0.5 |
Trichomonas vaginalis | malic enzyme, putative | 0.0014 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.