Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | malonyl-CoA decarboxylase | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | putative malonyl-CoA decarboxylase | 0.0504 | 0.4138 | 0.3814 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.1102 | 1 | 1 |
Onchocerca volvulus | 0.0414 | 0.3261 | 1 | |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.1102 | 1 | 1 |
Leishmania major | malonyl-coa decarboxylase-like protein | 0.0198 | 0.1141 | 0.5 |
Loa Loa (eye worm) | matrixin family protein | 0.0135 | 0.0523 | 0.0114 |
Brugia malayi | STAT protein, DNA binding domain containing protein | 0.0312 | 0.2253 | 0.1826 |
Onchocerca volvulus | 0.0414 | 0.3261 | 1 | |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0414 | 0.3261 | 0.297 |
Trypanosoma cruzi | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.0198 | 0.1141 | 0.5 |
Brugia malayi | Protein-tyrosine phosphatase containing protein | 0.0414 | 0.3261 | 0.2889 |
Trypanosoma cruzi | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.0198 | 0.1141 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0504 | 0.4138 | 0.3885 |
Trypanosoma brucei | malonyl-CoA decarboxylase, mitochondrial precursor, putative | 0.0198 | 0.1141 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | malonyl-CoA decarboxylase | 0.0504 | 0.4138 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.1102 | 1 | 1 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.1102 | 1 | 1 |
Loa Loa (eye worm) | STAT protein | 0.0312 | 0.2253 | 0.1919 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.