Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | carbonic anhydrase II | 0.1427 | 1 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0325 | 0.0221 | 0.0221 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.1427 | 1 | 1 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.0657 | 0.3161 | 0.3007 |
Schistosoma mansoni | calcium-activated potassium channel | 0.057 | 0.2393 | 0.2221 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1427 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.0221 | 0.0221 |
Leishmania major | carbonic anhydrase-like protein | 0.1427 | 1 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.1427 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1427 | 1 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0325 | 0.0221 | 0.5 |
Plasmodium falciparum | carbonic anhydrase | 0.0325 | 0.0221 | 0.5 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1427 | 1 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0657 | 0.3161 | 0.3007 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.1427 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0657 | 0.3161 | 0.3161 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.1427 | 1 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.1427 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.0221 | 0.0221 |
Schistosoma mansoni | hypothetical protein | 0.0657 | 0.3161 | 0.3007 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.0657 | 0.3161 | 0.3007 |
Loa Loa (eye worm) | hypothetical protein | 0.0325 | 0.0221 | 0.0221 |
Echinococcus granulosus | carbonic anhydrase II | 0.1427 | 1 | 1 |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Mus musculus | ChEMBL23 | 10890167 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.