Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | poly(ADP-ribose) glycohydrolase, putative | 0.0161 | 0.5 | 0.5 |
Trypanosoma brucei | poly(ADP-ribose) glycohydrolase, putative | 0.0161 | 0.5 | 0.5 |
Echinococcus multilocularis | poly(ADP ribose) glycohydrolase | 0.0161 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0161 | 0.5 | 0.5 |
Schistosoma mansoni | poly(ADP-ribose) glycohydrolase | 0.0161 | 0.5 | 0.5 |
Toxoplasma gondii | poly(ADP-ribose) glycohydrolase | 0.0161 | 0.5 | 0.5 |
Entamoeba histolytica | poly(ADP-ribose) glycohydrolase, putative | 0.0161 | 0.5 | 0.5 |
Echinococcus granulosus | polyADP ribose glycohydrolase | 0.0161 | 0.5 | 0.5 |
Loa Loa (eye worm) | Poly(ADP-ribose) glycohydrolase | 0.0161 | 0.5 | 0.5 |
Trypanosoma cruzi | poly(ADP-ribose) glycohydrolase, putative | 0.0161 | 0.5 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Ki (binding) | = 6 uM | Compound was evaluated for the inhibition of [125I]-labeled D-mannose-bovine serum albumin binding to alveolar macrophages | ChEMBL. | 7310815 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.