Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 41.8 % | Inhibition of tumor necrosis factor alpha release by endotoxin stimulated human peripheral blood mononuclear cells at 1e-4 M | ChEMBL. | 15743181 |
Inhibition (functional) | = 41.8 % | Inhibition of tumor necrosis factor alpha release by endotoxin stimulated human peripheral blood mononuclear cells at 1e-4 M | ChEMBL. | 15743181 |
Inhibition (functional) | = 95.3 % | Inhibition of Candida albicans at 100 microM concentration. | ChEMBL. | 12593664 |
Inhibition (functional) | = 95.3 % | Inhibition of Candida albicans colony forming units (CFU) at 1e-4 M compound | ChEMBL. | 15743181 |
Inhibition (functional) | = 95.3 % | Inhibition of Candida albicans at 100 microM concentration. | ChEMBL. | 12593664 |
Inhibition (functional) | = 95.3 % | Inhibition of Candida albicans colony forming units (CFU) at 1e-4 M compound | ChEMBL. | 15743181 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
2 literature references were collected for this gene.