Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0052 | 0.005 | 0.0058 |
Toxoplasma gondii | kinesin motor domain-containing protein | 0.0276 | 0.1127 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0244 | 0.0974 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0076 | 0.0166 | 0.0116 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0052 | 0.005 | 0.0058 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0052 | 0.005 | 0.0058 |
Plasmodium falciparum | kinesin-5 | 0.0276 | 0.1127 | 0.5 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0244 | 0.0974 | 1 |
Schistosoma mansoni | cyclic-nucleotide-gated cation channel | 0.0052 | 0.005 | 0.0058 |
Giardia lamblia | Kinesin-5 | 0.0276 | 0.1127 | 0.5 |
Brugia malayi | Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog | 0.0076 | 0.0166 | 0.107 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0166 | 0.107 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0261 | 0.1056 | 0.1011 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0261 | 0.1056 | 0.9344 |
Plasmodium vivax | kinesin-5 | 0.0276 | 0.1127 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0261 | 0.1056 | 0.1011 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0261 | 0.1056 | 0.9344 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0052 | 0.005 | 0.0058 |
Schistosoma mansoni | hypothetical protein | 0.1846 | 0.8675 | 1 |
Loa Loa (eye worm) | kinesin-like protein KLP2 | 0.0276 | 0.1127 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0285 | 0.1172 | 0.1351 |
Entamoeba histolytica | kinesin, putative | 0.0276 | 0.1127 | 0.5 |
Echinococcus multilocularis | kinesin family 1 | 0.2121 | 1 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0052 | 0.005 | 0.0058 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0166 | 0.0191 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0285 | 0.1172 | 0.1351 |
Echinococcus granulosus | voltage gated potassium channel | 0.0076 | 0.0166 | 0.0116 |
Echinococcus multilocularis | voltage gated potassium channel | 0.0076 | 0.0166 | 0.0116 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0076 | 0.0166 | 0.0116 |
Schistosoma mansoni | kinesin eg-5 | 0.0276 | 0.1127 | 0.1299 |
Brugia malayi | Kinesin motor domain containing protein | 0.0276 | 0.1127 | 1 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0076 | 0.0166 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.0891 | 0.7805 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | 0 | Activity at COX2 assessed as inhibition of arachidonic acid-induced PGE2 production in LPS-stimulated J774 cells | ChEMBL. | 17181159 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.