Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0119 | 0 | 0.5 |
Echinococcus multilocularis | indoleamine 2,3 dioxygenase 2 | 0.3262 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.1664 | 0.4918 | 0.4918 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0119 | 0 | 0.5 |
Loa Loa (eye worm) | indoleamine 2,3-dioxygenase | 0.3262 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.3262 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.1664 | 0.4918 | 0.4918 |
Schistosoma mansoni | hypothetical protein | 0.3262 | 1 | 1 |
Onchocerca volvulus | 0.0119 | 0 | 0.5 | |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.1602 | 0.4718 | 0.4718 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0119 | 0 | 0.5 |
Echinococcus granulosus | indoleamine 23 dioxygenase 2 | 0.3262 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.