Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | phosphorylase, glycogen, liver | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0117 | 0.4959 | 0.8342 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.013 | 0.5944 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.5936 | 0.5936 |
Mycobacterium tuberculosis | Probable reductase | 0.0117 | 0.4959 | 0.8342 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.5936 | 0.578 |
Schistosoma mansoni | glycogen phosphorylase | 0.013 | 0.5936 | 0.578 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.5936 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 1 | 1 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0056 | 0.0369 | 0.0621 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 1 | 1 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.013 | 0.5936 | 1 |
Giardia lamblia | Glycogen phosphorylase | 0.013 | 0.5936 | 0.5 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.5936 | 0.5 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.013 | 0.5936 | 0.5936 |
Echinococcus multilocularis | geminin | 0.0184 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.013 | 0.5936 | 0.5 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.5936 | 0.5936 |
Leishmania major | trypanothione reductase | 0.0051 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0117 | 0.4959 | 0.8342 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0 | 0.5 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0 | 0.5 |
Echinococcus multilocularis | glycogen phosphorylase | 0.013 | 0.5936 | 0.5936 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.013 | 0.5944 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.013 | 0.5944 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.013 | 0.5936 | 0.5 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0117 | 0.4959 | 0.8342 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.013 | 0.5936 | 0.5 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.013 | 0.5944 | 1 |
Brugia malayi | carbohydrate phosphorylase | 0.013 | 0.5936 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.013 | 0.5936 | 0.5936 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0056 | 0.0369 | 0.5 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0 | 0.5 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0117 | 0.4959 | 0.8342 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.013 | 0.5936 | 0.5936 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0 | 0.5 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.013 | 0.5936 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0117 | 0.4959 | 0.8342 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.